Research

We are interested in understanding how molecular networks within cells such as signal transduction cascades or gene regulatory networks process information.

We primarily study networks controlling cell growth and differentiation. Disfunction of these networks is involved in many diseases such as cancer. Many of our projects investigate epidermal growth factor receptor (EGFR) signalling, where we dissect the role of feedback regulation in robustness of signalling and drug resistance.

We are associated member of the Molecular Cancer Research Center at Charite, the graduate schools “Computational Biology” and “Berlin school of oncology” and the Network of Excellence “EpiGeneSys”.

Funding

We are funded primarily by BMBF, DFG and EU, which we greatfully acknowledge:

Current Funding

  • 2014-2016 Berlin School of Integrative Oncology, DFG
  • 2014-2016 Collaborative Project with Genentech Inc.
  • 2014-2016 SysDT Developmental Toxicity, BMBF
  • 2013-2015 OncoPath, BMBF E:Bio-Initiative, coordinator together with Christine Sers)
  • 2012-2016 Information flow in a mammalian signal transduction pathway, DFG SPP 1395/2
  • 2012-2016 ZiSS, BMBF
  • 2011-2015 Graduate School “Computational Systems Biology”, DFG

Past Funding

  • 2008-2014 FORSYS Young investigator programme, BMBF
  • 2010-2014 Bernstein Center, BMBF
  • 2010-2013 BactoCom, EU FP7
  • 2009-2013 Theoretical Biology, DFG, SFB 618
  • 2008-2011 CancerSys, EU FP7
  • 2009-2012 ColoNet, BMBF MedSys
Last modified:: 2017/03/13 18:02